Publications

 

Parkinson’s disease


  • 16.04.2013
    Gene therapy with CDNF provides functional benefits in a rat model of Parkinson's disease
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  • 04.02.2013
    Characterization of mammalian posttranslational modifications of GDNF
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  • 03.11.2011
    License agreement on sales of recombinant CDNF protein for research use
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  • 29.09.2011
    CDNF is both neuroprotective and neurorestorative in MPTP mouse model of Parkinson's disease
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  • 20.09.2011
    Professor Barry Hoffer comments on preclinical CDNF data from rodent models of Parkinson's disease
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  • 31.01.2011
    Data for chronic infusion of CDNF in rat model of Parkinson's disease
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  • 10.01.2011
    Syndecan-3 identified as a novel receptor for GDNF
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  • 03.11.2010
    MANF has a unique mechanism to rescue apoptotic neurons
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  • 10.11.2009
    Novel CDNF/MANF family of neurotrophic factors (new review article)
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  • 25.09.2009
    Regulation of Brain-Derived Neurotrophic Factor (BDNF) and Cerebral Dopamine Neurotrophic Factor (CDNF) by anti-Parkinsonian drug therapy in vivo
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  • 17.09.2009
    Constitutive Ret signaling is protective for dopaminergic cell bodies but not for axonal terminals
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  • 03.08.2009
    Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease
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  • 15.07.2009
    Heparin-binding determinants of GDNF reduce its tissue distribution but are beneficial for the protection of nigral dopaminergic neurons
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  • 02.01.2009
    The structure of the conserved neurotrophic factors MANF and CDNF explains why they are bifunctional
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  • 01.01.2009
    Evidence that DmMANF is an invertebrate neurotrophic factor supporting dopaminergic neurons
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  • 01.01.2009
    MANF is widely expressed in mammalian tissues and differently regulated after ischemic and epileptic insults in rodent brain
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Alzheimer’s disease and Neuroinflammation


  • 15.11.2009
    Physiological and pathophysiological outcomes of the interactions of HMGB1 with cell surface receptors
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  • 25.06.2009
    Inhibition of Acyl-coenzyme A: Cholesterol Acyl Transferase modulates amyloid precursor protein trafficking in the early secretory pathway
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  • 11.01.2009
    Neuronal regulation of immune responses in the central nervous system
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  • 11.01.2009
    Novel N-terminal cleavage of APP precludes Aβ generation in ACAT-defective AC29 cells
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Neurotrophins and Neuronal Plasticity


  • 09.02.2013
    Review on how antidepressants enhance neuronal plasticity
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  • 10.06.2012
    NPAS4 gene regulates plasticity in adult visual cortex
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  • 13.03.2012
    US Patent Office grants a patent on amblyopia therapy to Hermo Pharma
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  • 23.02.2012
    First patients completed the amblyopia phase 2a study
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  • 02.01.2012
    Fear erasure in mice requires synergy between antidepressant drugs and extinction training
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  • 09.11.2011
    Notice of Allowance for U.S. patent covering amblyopia treatment
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  • 03.01.2011
    An epigenetic mechanism involved in adult visual cortex plasticity
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  • 21.02.2010
    The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity
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  • 20.12.2009
    Role of Brain-Derived Neurotrophic Factor in the aetiology of depression: implications for pharmacological treatment
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  • 01.11.2009
    Neural plasticity and recovery from depression
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  • 30.06.2009
    Co-treatment with diazepam prevents the effects of fluoxetine on the proliferation and survival of hippocampal dentate granule cells
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  • 01.02.2009
    Chronic fluoxetine treatment increases expression of synaptic proteins in the hippocampus of the ovariectomized rat: role of BDNF signalling
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  • 03.08.2008
    The antidepressant fluoxetine restores plasticity in the adult visual cortex
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